Herpesvirus reactivation is associated with mortality in critically ill ICU patients with COVID-19: Insights from a retrospective single-center analysis of 455 cases

Critically ill patients with COVID-19 frequently develop viral reactivation. This retrospective single-center analysis of 455 cases examined the clinical significance of herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV) reactivation in ICU patients with COVID-19, finding associations between herpesvirus reactivation and increased mortality outcomes.